The PharmGKB is a pharmacogenomics (PGx) knowledge resource that encompasses clinical information including dosing guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships. PharmGKB pathways are evidence-based diagrams detailing the pharmacokinetics (PK) or pharmacodynamics (PD) of a PGx-relevant drug, accompanied by text providing background on the drug and a discussion of its PK, PD and PGx. The Pharmacogenomics Knowledgebase (PharmGKB) is an integrated online knowledge resource for the understanding of how genetic variation contributes to variation in drug response. PharmGKB数据库 PharmGKB（Pharmacogenetics and Pharmacogenomics Knowledge Base）是一个由美国国立卫生研究院（NIH）资助的药物基因组学知识库，旨在为临床医生和研究人员提供有关人类遗传变异如何影响药物反应的知识。 The Pharmacogenetics Knowledge Base (PharmGKB; ) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. PharmGKB（Pharmacogenetics and Pharmacogenomics Knowledge Base）是一个由美国国立卫生研究院（NIH）资助的药物基因组学知识库，旨在为临床医生和研究人员提供有关人类遗传变异如何影响药物反应的知识。 PharmGKB数据库（Pharmacogenetics and Pharmacogenomics Knowledge Base，药物遗传学和药物基因组学知识库）是目前最权威最完善的药物基因组专用数据库。 PhramGKB由美国国立卫生研究院（NIH）创建，收录了有关人… PharmGKB is a registered trademark of HHS and is financially supported by NIH/NHGRI/NICHD/NIDA/NCI. PharmGKB is managed at Stanford University (U24HG010615). ©2001- 2026. We are excited to announce that over the coming weeks, PharmGKB will officially become ClinPGx. Once the new ClinPGx website debuts, there will be a brief period where both websites will co-exist. If you’re looking to dig deeper into the science of pharmacogenomics, the PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information including clinical guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships.